2. Signaling Pathways
  3. PROTAC
  4. Ligands for Target Protein for PROTAC
  5. Ligands for Target Protein for PROTAC Control

Ligands for Target Protein for PROTAC Control

Ligands for Target Protein for PROTAC Controls (7):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-49421
    BTK ligand 12 1791402-91-9
    BTK ligand 12 is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs). BTK ligand 12 can serve as an active control for the target protein ligand of NRX-0492 (HY-153357).
    BTK ligand 12
  • HY-107443A
    (R)-I-BET762 carboxylic acid 1786401-70-4
    (R)-I-BET762 carboxylic acid, the R-enantiomer of I-BET762 carboxylic acid (HY-107443). I-BET762 carboxylic acid is an I-BET762-based warhead ligand for conjugation reactions of PROTAC targeting on BET. I-BET762 carboxylic acid is a BRD4 inhibitor with a pIC50 value of 5.1.
    (R)-I-BET762 carboxylic acid
  • HY-169439
    Temozolomide-amino hydrochloride 449187-98-8
    Temozolomide-amino hydrochloride (compound 8) is an activity control for the target protein ligand of Naph-Se-TMZ (HY-169433).
    Temozolomide-amino hydrochloride
  • HY-169375
    RSL3-4-Me 3049087-33-1
    RSL3-4-Me is the active control of the target protein ligand Demethyl-RSL3 (HY-135832), which can be used for the synthesis of PROTAC .
    RSL3-4-Me
  • HY-168662
    Palbociclib-CH2COOH 2139329-57-8
    Palbociclib-CH2COOH is a Ligands for Target Protein for PROTACs. Palbociclib-CH2COOH can serve as an active control for the target protein ligand of CPD-39 (HY-168664) and CPD-10 (HY-168660).
    Palbociclib-CH2COOH
  • HY-170317
    EA-89-Succinic acid
    EA-89-Succinic acid (Compound 26) is the active control of the target protein ligand EA-89 (HY-170314), which can be used for the synthesis of PROTAC .
    EA-89-Succinic acid
  • HY-168202
    CCS1477a
    CCS1477a is the active form of the target protein ligand of PROTAC degrader MJP6412 (HY-168201).
    CCS1477a